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Organic Chemist
Posted: 06/14/25
2025-06-06
2025-07-14
Employment Type:
Full-Time
Job Number: EB-1466892038
Job Description
Position: Organic Chemist
Direct Hire
Location: San Diego, CA
About the position:
Our Client is seeking an experienced Synthetic Organic and/or Process Development R&D Chemist in San Diego. The candidate will spearhead chemical reaction discovery and chemical process development to convert biologically-derived intermediates into sustainable, industrial chemical products. The candidate will need to perform both in lab experiments and detailed dry-lab planning.
Key Responsibilities:
● Design and demonstrate novel multistep chemical syntheses to produce our Client's target compounds.
● Perform discovery reactions with full characterization of all byproducts to quantify reaction performance.
● Implement HPLC, GC, MS, TGA, and other relevant analytical techniques to determine reaction products and byproducts.
● Perform reaction optimization DBTL cycles to optimize: conversion, yield, solvent selection, operating conditions, and product recovery.
● Identify and apply heterogeneous catalysts for diverse reactions.
● Identify appropriate equipment needed for our client to expand its R&D and Pilot Lab Chemistry footprint.
● Perform heterogeneous hydrogenation and hydrodeoxygenation reaction discovery and process development.
● Identify and evaluate appropriate industrial protection groups amendable to massive-scale production.
● Perform aromatic modification reaction discovery and development.
● Evaluate and implement chemical process product purification techniques including crystallization, liquid-liquid extraction, precipitation, filtration, and distillation.
● Scale product recovery techniques to Pilot Lab unit operations.
● Leverage knowledge of organic chemistry to design multistep synthetic routes that maintain carbon skeletons and stabilize molecules.
● Apply knowledge of both batch and flow chemistry to develop novel reactions and optimize conditions.
● Lead interactions with CROs, in parallel with in-house experiments, to rapidly develop chemical processes and to gather additional analytical datasets.
● Exemplify excellence in lab safety and chemical hygiene practices.
● Strengthen and expand both chemistry data and project management to streamline communication in Our Client's’s R&D team.
● Organize, present, and share data, challenges, questions, and strategies with Our Client's’s global team.
Qualifications:
●Minimum Bachelor’s Degree in Chemistry, or equivalent area, from an accredited university. (Masters or PhD preferred)
*8-10 yrs of experience in the field.
● Experience performing research discovery work to develop multi-step enzymatic synthesis.
● Experience optimizing yield, reaction time, selectivity, conversion, and solvent selection for chemical reactions.
● Experience with heterogeneous catalyst and product recovery.
● Experience with hydrogenation, deoxygenation, protection/deprotection, and ring-rearrangement chemistry.
● Experience transferring/scaling multi-step synthesis to pilot scale.
● Experience development analytical methods on GC, HPLC, MS, and/or TGA.
● Experience developing product isolation/purification/crystallization/extraction methods.
● Experiencing implementing, organizing, and executing project management strategies for communication and transfer of chemistry data and reaction conditions.
● Additional experience to support key responsibilities above.
Working Conditions:
Environment
● Able to work 5 days a week onsite.
Direct Hire
Location: San Diego, CA
About the position:
Our Client is seeking an experienced Synthetic Organic and/or Process Development R&D Chemist in San Diego. The candidate will spearhead chemical reaction discovery and chemical process development to convert biologically-derived intermediates into sustainable, industrial chemical products. The candidate will need to perform both in lab experiments and detailed dry-lab planning.
Key Responsibilities:
● Design and demonstrate novel multistep chemical syntheses to produce our Client's target compounds.
● Perform discovery reactions with full characterization of all byproducts to quantify reaction performance.
● Implement HPLC, GC, MS, TGA, and other relevant analytical techniques to determine reaction products and byproducts.
● Perform reaction optimization DBTL cycles to optimize: conversion, yield, solvent selection, operating conditions, and product recovery.
● Identify and apply heterogeneous catalysts for diverse reactions.
● Identify appropriate equipment needed for our client to expand its R&D and Pilot Lab Chemistry footprint.
● Perform heterogeneous hydrogenation and hydrodeoxygenation reaction discovery and process development.
● Identify and evaluate appropriate industrial protection groups amendable to massive-scale production.
● Perform aromatic modification reaction discovery and development.
● Evaluate and implement chemical process product purification techniques including crystallization, liquid-liquid extraction, precipitation, filtration, and distillation.
● Scale product recovery techniques to Pilot Lab unit operations.
● Leverage knowledge of organic chemistry to design multistep synthetic routes that maintain carbon skeletons and stabilize molecules.
● Apply knowledge of both batch and flow chemistry to develop novel reactions and optimize conditions.
● Lead interactions with CROs, in parallel with in-house experiments, to rapidly develop chemical processes and to gather additional analytical datasets.
● Exemplify excellence in lab safety and chemical hygiene practices.
● Strengthen and expand both chemistry data and project management to streamline communication in Our Client's’s R&D team.
● Organize, present, and share data, challenges, questions, and strategies with Our Client's’s global team.
Qualifications:
●Minimum Bachelor’s Degree in Chemistry, or equivalent area, from an accredited university. (Masters or PhD preferred)
*8-10 yrs of experience in the field.
● Experience performing research discovery work to develop multi-step enzymatic synthesis.
● Experience optimizing yield, reaction time, selectivity, conversion, and solvent selection for chemical reactions.
● Experience with heterogeneous catalyst and product recovery.
● Experience with hydrogenation, deoxygenation, protection/deprotection, and ring-rearrangement chemistry.
● Experience transferring/scaling multi-step synthesis to pilot scale.
● Experience development analytical methods on GC, HPLC, MS, and/or TGA.
● Experience developing product isolation/purification/crystallization/extraction methods.
● Experiencing implementing, organizing, and executing project management strategies for communication and transfer of chemistry data and reaction conditions.
● Additional experience to support key responsibilities above.
Working Conditions:
Environment
● Able to work 5 days a week onsite.
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